Neuroimaging features in Wolfram syndrome type 1

Neurol Sci. 2024 Jan 31. doi: 10.1007/s10072-024-07352-8. Online ahead of print.


Wolfram syndrome type 1 is a rare autosomal recessive genetic disorder which is characterized by the co-existence of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness, and hence is also referred to as the acronym DIDMOAD. In this neuroimage, the typical neuroimaging features of a genetically confirmed case of Wolfram syndrome type 1 are presented. The presence of left-sided vestibulocochlear dysplasia is a novel finding in our case which has not been reported previously.

PMID:38291196 | DOI:10.1007/s10072-024-07352-8