Leber hereditary optic neuropathy: update on genetics and pathomechanisms

J Fr Ophtalmol. 2022 Nov;45(8S1):S17-S23. doi: 10.1016/S0181-5512(22)00446-6.


Leber Hereditary Optic Neuropathy is still a dramatic disease of optic nerve. Origins and mechanisms are extensively studied in the last decades, in link with emergent therapeutic approaches. This article is an update on genetics and pathophysiology of LHON and leber-like inherited optic neuropathies.

PMID:36529473 | DOI:10.1016/S0181-5512(22)00446-6