A Rare Case of Wolfram Syndrome Presenting With Tuberculous Meningitis: A Case Report

Clin Case Rep. 2025 Jan 16;13(1):e70116. doi: 10.1002/ccr3.70116. eCollection 2025 Jan.

ABSTRACT

Wolfram syndrome is an extremely rare condition composed of a tetrad of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. When concurrently presenting with another condition, such as tuberculous meningitis, the widespread range of resulting symptoms delays the establishment of diagnosis and treatment, which results in increased patient morbidity.

PMID:39822882 | PMC:PMC11736699 | DOI:10.1002/ccr3.70116